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Shingles : Symptoms and Causes


Early treatment can shorten the duration of the infection and reduce the risk of complications.

◉ Stages of shingles

Most cases of Shingles last about three to five weeks.


◉ Causes

The varicella-zoster virus is a strictly human virus belonging to the Herpesviridia family.

After the primary infection, the VZV virus remains in a latent state in the sensory nerve ganglia. This may not cause problems for many years. But as the person ages, the virus can reactivate, traveling back down the long nerve fibers that run from the sensory cell bodies to the skin. The viruses multiply, the telltale rash breaks out, and the person now has Shingles.

It is not known exactly why the shingles virus is reactivated later in life, but most cases are thought to be caused by reduced immunity.

Shingles

◉ Shingles Risk Factors

Anyone who has had chickenpox is at risk of developing Shingles. Factors that may increase your risk of developing Shingles include:

  • Advanced age: The risk increases with age. About half of all shingles cases occur in adults 60 years of age or older.
  • Diseases that weaken your immune system, such as HIV and cancer, can increase the risk of shingles.
  • Immunosuppressive treatments, radiotherapy or chemotherapy can reduce your resistance to diseases and trigger shingles.
  • Your immune system may be weaker when you have an infection or are under stress (both physical and emotional stress).

Note :

  • Most people only get shingles once. However, it is possible to have it more than once.

◉ Is Shingles contagious ?

You can't get Shingles from someone who has Shingles, but you can get Chickenpox.

Direct contact with fluid from a Shingles rash can still spread the varicella zoster virus, which can cause chickenpox in people who have never had chickenpox before or the chickenpox vaccine.


◉ What are the symptoms of Shingles ?

Usually, Shingles is unilateral, the infection develops on only one side of the body or face and in a small area. The most common place where Shingles occurs is a band, called a dermatoma, that runs down one side of the trunk around the waist.

Before the rash appears, people often feel pain, itching, or tingling in the area where it will develop. This may occur several days before the rash appears.

Most people with shingles have one or more of the following symptoms:

  • A red rash that begins a few days after the pain.
  • Fluid-filled blisters that break open and form a crust.
  • Burning, tingling, itching, shooting pain or numbness of the skin.
  • Touch sensitivity.
  • Chills, fever, fatigue, headache or stomach pain.

Note :

  • The rash does not always appear red. Depending on skin tone, the rash may appear dark pink, dark brown, or purplish.
  • The pain can be intense. Depending on where the pain is located, it can sometimes be confused with heart, lung or kidney problems.
  • Some people experience the pain of Shingles without ever developing the rash.

Ophthalmic Shingles

If you notice blisters on your eye, see your doctor immediately as this is an urgent issue. Without treatment, ophthalmic Shingles can lead to serious problems, including long-term vision loss and permanent scarring from corneal swelling.


Shingles on the face

Shingles can develop on one side of your face. The infection can lead to:

  • Weakness in your facial muscles
  • Hearing problems
  • Difficulty eating, sores lesions can be very painful
  • Shingles on the scalp can lead to permanent bald patches.
Zona

Long term pain

After the Shingles rash goes away, some people may experience persistent pain called postherpetic neuralgia. The pain is felt in the area where the rash has occurred. The older you are when you have Shingles, the more likely you are to develop postherpetic neuralgia.


Sources

  1. Cong Tri Tran et al - Zona : risques et prévention sous immuno-modulateurs
  2. J.Gaillat - Zona
  3. S. Mathis et al - Le zona et ses complications neurologiques
  4. Tonya M et al - Shingles: Not Just a Rash
  5. mayoclinic - Shingles
  6. CDC- Shingles (Herpes Zoster)
  7. medlineplus - Shingles
  8. healthline - Shingles: Everything You Should Know
  9. nhs inform - Shingles
  10. National Institute on Aging - Shingles
  11. CHU de Angers - VIRUS de la VARICELLE et du ZONA (VZV)